J. Mitra Chikungunya IgM Card

Chikungunya virus (CHIKV) is an insect-borne virus, of the genus Alphavirus, that is transmitted to humans by virus-carrying Aedes mosquitoes. There have been recent breakouts of CHIKV associated with severe illness. CHIKV causes an illness with symptoms similar to dengue fever. CHIKV manifests itself with an acute febrile phase of the illness lasting only two to five days, followed by a prolonged arthralgic disease that affects the joints of the extremities. The pain associated with CHIKV infection of the joints persists for weeks or months, or in some cases years. As clinical symptoms & signs of this infection resemble those of many other infectious diseases including Dengue fever, clinical findings need to be confirmed by laboratory diagnostic techniques.

Advantage chikungunya igm card is one step immunochromatographic assay. The test sample is introduced to and flows laterally through an absorbent pad where it mixes with the conjugate. If the sample contains Chikungunya specific IgM antibodies, it forms a complex with the chikungunya antigen gold colloid conjugate. The complex then migrates through the nitrocellulose membrane by caplillary action. When the complex meets the line of immobilized Antihuman IgM antibodies (Test line, ‘T’), it generates a pink purple line, indicating that the sample is reactive. To serve as a procedural control, an additional control line ‘C’ has been immobilized at a distance from the test line on the strip. If the test is performed correctly, this will result in the formation of a pinkish-purple line at the control region upon contact with the conjugate.